Bivalent COVID boosters are available & exciting

An article I read in the New York Times says that many Americans aren’t even noticing that the new, bivalent COVID-19 vaccines are now available. The public has lost interest in all things coronavirus, and the government is running out of funding for effective reminders or elaborate, coordinated delivery campaigns.

It falls to us, concerned citizens, to spread the word about how we can protect ourselves and others. In the interest of fighting misinformation, I will also share reputable resources for those wishing to do their own research.

The new boosters, authorized by the F.D.A. last month, are “bivalent” because they protect against:

  1. the Omicron subvariant still circulating in addition to
  2. the original version of the COVID-19 virus.

The Latin root bi– means two.

Merriam Webster dictionary page highlighting prefix definition of BI means TWOPut simply, a single shot now offers two kinds viral defense: more of the same protection from the original booster, plus, for the first time, the specific power to fight Omicron. That named strain of the virus, also known as lineage B.1.1.529, caused the enormous spike in coronavirus cases early in 2022. It’s estimated that the “mild” Omicron strain was responsible for killing 117,560 people in America. Source: MedRxiv.

More than one million Americans have died from COVID-19 since the pandemic began. This virus has been far deadlier than any recent influenza outbreak. The worst annual flu statistics in the past decade saw 52,000 people die in the US, for comparison, while an average year sees  ≈34,000 flu deaths. Source: CDC.

Allow me to do the math for those who struggle with the subject: with COVID-19 having a major impact over the past three years, one million lost lives (1,000,000) averages out to roughly 333,000 American deaths in a single pandemic year. (1,000,000 ÷ 3 = 333,333 ¹⁄3) This means COVID kills 10× as many as an average annual flu does in the U.S.A.

  • 34,000 × 3 = 102,000 this is how many flu would probably have killed over three years
  • 102,000 × 10 = 1,020,000 this is how many flu would probably have killed if it were 10 times worse
  • 1,020,000 is close enough to one million to be considered the same for this kind of analysis

Flu vs. COVID death rate comparisons are usually the work of the innumerate… or liars.

It’s vaccination, not vaccines, that saves lives.

Personally, I’m with Zeynep Tufekci, whose opinion piece in the Times marveled at the awesomeness of vaccination’s potential… while exploring the inadequacy of current messaging to motivate our citizens.

Tukekci writes: “[I]t’s vaccination, not vaccines, that saves lives.”

And she’s right about that.

bandage on upper armThe most impressive technology can solve no problem if it isn’t deployed where it is needed and at the right time. Safe, modern, effective vaccine boosters against COVID are being provided at no cost by the U.S. government. Those shots are available today.

As of now, everyone over age 12 in America is entitled to a free bivalent booster shot as long as at least two months have passed since the most recent dose.

Boosters reduce your chance of catching Omicron, and they substantially reduce an infected person’s risk of being hospitalized with—or dying of—COVID-19. Sources: New England Journal of Medicine, CDC, United Kingdom Health Security Agency.

Boosters will also help you avoid long COVID. Source: JAMA.

Aside from spreading personal misery, long COVID is also costing our economy hundreds of billions of dollars, with just lost wages from the disease estimated between $170-230 billion annually. Note that this figure approaches 1% of the total U.S. gross domestic product. Sources: World Economic Forum, Brookings Institution, Federal Reserve Bank of MN

Getting vaccinated and boosted is a patriotic choice as doing so protects our faltering economy.

I was delighted to take my teen in for a bivalent booster dose this week. His previous shot was last winter, he attends classes in person while being the only kid in most rooms electing to mask, and our household includes a high risk loved one. A few hours with a sore arm and one long nap later, my child has no lingering side effects, but he can more safely spend time with his grandparent.

There’s no way to put a price on the value of those hours. COVID vaccines are a miracle, a blessing, and quite literally wonderful.

The rest of my family will be getting bivalent boosters soon, having had age- and risk-related doses more recently than a healthy teen.Redacted official CDC COVID-19 Vaccination Record Card

Opting in for your bivalent booster dose is choosing life over death, wellness over infirmity, civic engagement over cynicism, and family values over selfishness. Vaccination protects our society by safeguarding both individual health and overall economic function; sick people are less productive.

I’m fully vaccinated—and boosted—because I love America, and because my religion teaches that life is a sacred gift.

What’s your reason?

Season’s Greetings to all people of goodwill

Season’s Greetings to All!

I’d like to offer a Merry Christmas to everyone celebrating today, but also Warm Winter Wishes to the rest.Mom's idea of a restrained Xmas with dozens of gifts piled high under tall tree

I believe we all win when we give others the benefit of the doubt: if I tell you Happy Holidays instead of Merry Christmas, I don’t intend to denigrate your savior. Instead, I hope you recognize that my own beliefs differ, but you have my respect for your Joyeux Noël.

My favorite Christmas lyric is “peace to men of goodwill!” May this message find every reader safe, secure, feeling cozy and full of joy.

A December 23rd article in the New York Times informed me that for many—especially women, people aged 18-44, and independents or Republican voters with modest incomes—2021 might be the source of even more stress over the holidays than 2020.

So many are exhausted and demoralized.

I immediately sent a text to my sister-in-law upon reading that story. I thanked her for all that she does, especially when I’m on the other side of the country, and told her how grateful I am that she married into our family. What a delight to enjoy—and like!—one’s relatives.

It’s easy to overlook kindness when life feels hectic. Extending a hand to someone else is a surprisingly effective way to find one’s own balance.

Let someone know they are appreciated today, and perhaps you can ease some of that holiday stress afflicting a loved one or yourself. If your home is beautifully decorated or you’re dining in relative splendor, make sure whoever provided such bounty to you knows it matters.

And offer to do the tidying up if someone else arranges most of your holiday cheer! A shout out to my kids who washed all the dishes after our festive dinner last night.

For all that I am firmly aware of the rising caseload of the Omicrom variant, and the lingering specter of inflation punishing our pocketbooks, December of 2021 offers good news that I feel compelled to acknowledge. Let’s look at those sunny spots on the horizon.

Without being totally divorced from reality, it is definitive that we are seeing some of the highest daily COVID-19 case rates of the entire pandemic. I agree that this sucks! Omicrom is a rip-roarin’ beast of infection; it’s many times more infectious than Delta, which superseded those original strains of SARS-CoV-2 from early 2020.

In spite of that ugly, hospital-cramming fact, the amazing step forward of mRNA vaccinations means that the novel coronavirus is now, finally, actually only approaching the flu in terms of order of magnitude of lethality.

According to David Leonhardt’s Dec. 23rd article in the New York Times, here’s some hard data on the current degree of risk from COVID-19:

The risks here for older people are frightening: A rate of 0.45 percent, for instance, translates into roughly a 1 in 220 chance of death for a vaccinated 75-year-old woman who contracts Covid.

You’ll want to view the article to see its excellent graphs to get the fullest picture.
That is frightening, but what about when we consider other common ailments? From the same article:

One reassuring comparison is to a normal seasonal flu. The average death rate among Americans over age 65 who contract the flu has ranged between 1 in 75 and 1 in 160 in recent years, according to the C.D.C.

Until I read this story, I wasn’t aware that COVID-19 has become, for a vaccinated senior citizen, less deadly than an average flu. What a powerfully reassuring data point! I find this a reason for great hope.

bandage on upper arm

Before I go on, allow me to make obvious this other point: the unvaccinated are not nearly so safe. COVID-19 is much deadlier for the unvaccinated than flu is.

The last flu outbreak to kill millions, plural, was the “Asian flu” of the mid-1950’s, with a total death count estimated around 2 million souls worldwide.

An otherwise similar unvaccinated elderly woman is 13 times more likely to die of COVID than the vaccinated hypothetical person above. There remains a much, much higher probability of death for that unvaccinated 75 year old woman than she would face in a typical flu season.

COVID-19 leaped onto the charts as the third leading cause of death for Americans in 2020, and the elderly bear the brunt of this burden. We lost 1.8 years of life expectancy last year; that’s the worst decline in over 70 years, since WWII saw so many killed between 1942-43.

It is wonderful that we’re moving toward taming the novel coronavirus from killer of millions to “only” fatal to hundreds of thousands. While not enough, that is good, and it should be appreciated…when it actually happens.

As of November 22, we’d lost more Americans in 2021 than we did in 2020. No one should ever forget that.

Yet savor the positive news as much as you dwell on the negative and your life will be better. If you are fortunate enough to have been vaccinated, your personal risk now pales compared to those who’ve mostly been tricked out of taking a life-saving inoculation

happy face smile
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In addition to the lifesaving wonder of vaccines that measurably reduce deaths amongst our most vulnerable population, we’ve also seen two new drugs approved as treatment options for COVID-19 in the USA this week. Where the latest variant has rendered ineffective some of our most effective earlier therapies, these new treatments arrive just in time.

They could also save us a lot of money.

To have new treatments people can self-administer at home—thus sparing exhausted, overburdened hospital staff while our total case numbers reach record heights—is another blessing. It’s hard for me to quantify how much I would prefer to pick up a prescription from my local pharmacy for a few days’ worth of pills if I had COVID over making repeated visits to a hospital or clinic.

The antiviral COVID pills from Pfizer and Merck will initially cost the federal government around $700 per dose. This represents an enormous savings spread over millions of doses vs. pricier monoclonal antibody treatments all of which cost $1200 or more at the heavily discounted government bulk purchase rate.Pile of money
Patients will also be spared unpredictable fees for visiting those staffed locations necessary to administer IV therapies. In an era of high inflation—and personally facing a mandatory switch to a new health insurance plan from a different provider starting January 1st—I find this a great relief.

I’ve never had a confusing or even shocking bill after visiting a pharmacy, unlike every time I’ve been a patient at a hospital. Reflecting on the fact that I’m so incredibly privileged that I’ve never had a gap* in my insurance coverage, it seems likely that others fear surprise bills far more than I do.

The pandemic isn’t over. Thoughtful individuals should still be wearing masks and making efforts to improve ventilation while meeting with those outside their households. That said, we understand more than ever about how COVID-19 spreads. Many of us are vaccinated, thus protected against the worst outcomes of the disease. Available treatments have expanded from desperate guesses to multiple effective therapeutics.

This ugly, lonely, uncomfortable period in history will end, though those of us who’ve lived through it may well spend the rest of our lives processing the experience. For example, many of us grew up with grandparents whose behavior was permanently affected by surviving the Great Depression.

Right now, on Christmas Day, 2021, I encourage you to look for the positive anywhere you can. Experiencing terrible events isn’t the only predictor of future suffering; so is how one responds to those challenges, and what one makes with the memories.

Things could be better, but, of course, they could also be worse. Having made it to my father’s house and remained in good health in spite of the journey, I find so much to celebrate this year.

May all these little celebrations be less fraught in 2022.

Wishing every reader good health, good cheer, and a large measure of optimism for the year ahead!

It was a painfully frustrating message replete with disinformation from an old friend the other day that prompted me to research and think about these comparisons. For the vaccinated, COVID may now be similar to a “mere” flu; for the unvaccinated elderly, endemic COVID-19 is still a virulent threat to be taken seriously.

Publicly available data makes all of this very clear. In 2020, 3 million people died from COVID-19. In a usual year, flu kills between 290,000 and 650,000 around the world. No math degree is required to calculate that somewhere in the ballpark of four to 10 times as many deaths occurred in 2020 than we would have expected from “mere” influenza.

The two most commonly prescribed antibody treatments, those made by Eli Lilly and Regeneron, don’t work against the Omicrom variant. Only GlaxoSmithKline’s sotrovimab—the most recently approved monoclonal antibody therapy—offers protection from Omicrom. These therapies cost thousands of dollars per dose (retail of ~$3000-5000 according to this news story, though other sources state that the federal government bought in bulk for $2100 per Regeneron dose and $1250 each for Eli Lily’s) and are administered intravenously, requiring a trained health care professional’s presence for every dose.

*Though the Affordable Care Act has led to a major increase in how many Americans have health insurance at any given time, in 2020, 9.5% had some coverage but also experienced a “gap” in continuous care, whereas another 12.5% remained completely uninsured.

Please donate blood soon if you’re able

The American Red Cross has issued an urgent plea: our hospitals are facing a severe blood shortage. Blood donors are desperately needed, not just today, but on an ongoing basis over the coming weeks.

“Right now, the supply of the sorely needed type O blood would last only a half-day.”

It takes time to process donated blood, the result is perishable, and the need never subsides. We have no artificial substitute for life-saving donated blood.

Per the Red Cross website, you can donate blood as often as every 56 days if you meet these criteria:

  • You must be in good health and feeling well
  • You must be at least 16 years old in most states
  • You must weigh at least 110 lbs

You can donate blood after any of the COVID-19 vaccinations currently approved in the United States, usually without delay. Expect to report exactly which vaccine you were given—Moderna, Pfizer, or Johnson & Johnson—and the date of your shot.

According to the Boston Globe:

“…[N]ormally the Red Cross nationwide has a five-day supply of all types of blood — meaning that if blood collections suddenly stopped altogether, there would be enough to last five days.

Right now, the supply of the sorely needed type O blood would last only a half-day.”American Red Cross logo

If you are healthy and able, please consider donating blood in the near future. Less than 38% of Americans are eligible to donate, and only about 3% of that group does so.

A single blood donation can save as many as three lives. It’s hard to imagine a more valuable use of one hour of one’s time.

Homebound senior wants COVID vaccine yet can’t get shot doctor prescribed

Here’s the story of one elderly American citizen who agreed to be vaccinated against COVID-19, yet hasn’t been able to receive a shot as of mid-June, 2021.

Someone I care about has a very complex medical situation. Her health is fragile, and her immune system is compromised.

My loved one is frail and almost completely housebound; it is a struggle even to get her to scheduled doctors’ appointments with ample notice. Sometimes, her body simply won’t conform to the constraints of sitting in a passenger vehicle. Hospital bed in dining room

She certainly would not be able to wait 30 minutes on a hard chair in a physician’s practice—let alone standing in an aisle at a local pharmacy—the way my kids and I did after our jabs. At the same time, due to a history of severe allergic reactions to drugs and vaccine components, the risk of an adverse reaction is higher than average for this patient.

Consultations with her various specialists resulted in a consensus that the Pfizer product is the only recommended COVID-19 vaccine for her.

Thus far, none of her providers has been able to offer access to a prescribed dose of COVID-19 vaccine during a routine visit. Internet-savvy family members continue searching for a solution that will accommodate her specific needs with no luck to date.

The patient’s state of residence now offers at-home vaccinations for those who are homebound. Unfortunately, the program sends its providers out with the Johnson & Johnson single dose vaccine only. According to the toll-free hotline, there are no exceptions unless the patient is under 17 years old.

This patient, though unable leave home for a shot, cannot take advantage of her state’s offering for housebound residents. According to the Journal of the American Medical Association, approximately 6% of U.S. seniors were completely or mostly homebound as of 2015.

Without a doubt, American wealth and power has provided a tremendous benefit to average citizens who’ve been amongst the earliest to access life-saving vaccines against the novel coronavirus. Public health, however, relies upon the breadth of its network to protect every resident. Many of our most vulnerable are still waiting as vaccines near expiration dates in medical center freezers.

Evidence of widespread vaccine hesitancy proves we must keep working to remove barriers to access for those willing, yet unable, to be vaccinated in currently available settings. Lives—and our loved ones—depend upon it.

Honestly admit vaccine side effect costs & better support the “hesitant” to increase compliance

When you get your COVID-19 vaccination—and I’d argue that approximately 99% of those reading this post have a moral imperative to do so—a realistic assessment of the facts suggests that you are likely* experience some uncomfortable side effects though they may be very mild.

News coverage, even in sources specifically geared toward those of us living with chronic conditions, heavily emphasizes the societal good which vaccination will bring—which is real enough—but most writers lean too heavily toward cheerleading at the expense of offering valuable information people need to cope with the particular pressures of their own individual lives.

I would like to stress that those of us more vulnerable than average to infirmity should plan for several days of being less effective in our work and daily lives after vaccination. It’s better to be prepared than to be caught flat-footed after the fact.

Politicians and business leaders who want the economy to boom should be offering solutions to make such preparations possible for the millions of Americans living in and at the edge of poverty who can’t afford to construct such safeguards for themselves.

Roughly 30 million American adults want to take the COVID-19 vaccine but haven’t yet managed to actually get the shot(s). Closer to 28 million are instead “vaccine hesitant,” stating they would probably or definitely not get vaccinated.Redacted official CDC COVID-19 Vaccination Record Card

Sufferers of autoimmune disease, getting your jab may well bring on a flare. That was my experience after my first dose, and I’m glad I dug down far enough through coy, dissembling news coverage and popular health reporting to be forewarned about the risk.

Here’s one published case study in The Lancet regarding the health of one gentleman with rheumatoid arthritis after getting the BioNTech-Pfizer vaccine. This article on Creaky Joints is the most honest that I read, speaking directly to specific reactions people with autoimmune conditions might expect.

I would take that first dose again, however, and I did return for my second shot of the Moderna vaccine.

I began composing this post whilst “enjoying” the resultant joint pains, exhaustion, and headache that came with full vaccination. Dose two also induced half a day of resounding nausea that could have been an exaggerated version of the queasiness I routinely get when very tired.

Side effects from the second shot prevented me from my normal activities—already constrained by my autoimmune disease diagnosis—for about two and a half days.

I.e., I would not have felt safe driving for at least two days after my second shot, nor would I have been healthy enough to go to work.

By comparison, after my first jab, I experienced sudden onset of extreme fatigue, headache, and an odd sensation I only associate with coming down with a virus that I can best describe as “the spaces in my joints feeling stretched out and wobbly.”Analog wall clock showing 12:06

Those shot #1 symptoms popped up about six hours after I received it mid-morning. I went to bed early, and the next day, all the viral infection type side effects were far less troublesome. I felt less than 100% the day after, but able to partake in most normal activities.

I.e., I could have worked through the side effects triggered by my first dose.

My arm ached significantly for a total of five or six days, however, and I developed an uncomfortable swollen feeling in my armpit several days later that was probably my lymph nodes reacting.

On the other hand, in the four weeks after my first dose of Moderna’s vaccine, I experienced the most significant stiffness, joint pain, swelling, and fatigue that I’d had since the pandemic began. Staying at home most of the time while society remained mostly shut down was generally very protective for me against my usual, recurrent autoimmune disease symptoms.

I used far less pain medication than usual between March of 2020 and April 2021. I went entire weeks without needing an NSAID anti-inflammatory or using prescription pain killers. Between my two doses of COVID-19 vaccine, I required at least one of those every day.

I.e., I would have struggled to meet the demands of a full time job plus family responsibilities on many of the days between my first and second vaccine injections.Prescription bottle of pain pills

It is worth noting that this potentially vaccine-provoked flare never reached peaks equivalent to the worst ones I had right after my diagnosis. Also, the flare absolutely could have been coincidental. But, again, it’s the only serious one I had through the entire pandemic right up until I got my first shot.

I’m not arguing against vaccination. I am suggesting some of us might need extra resources to meet our daily responsibilities when we elect vaccination, doing our part to protect the entire community. Stepping up comes with a cost.

I have a healthy, supportive spouse. My large family includes relatively helpful, fit teens able to pick up the slack with household chores. Family members have been able to stagger vaccine appointments so we never experienced side effects simultaneously. Our income is sufficient that purchasing takeout meals or prepared foods is not a burden. I am easily able to reach my regular doctor with any concerns because I’m well-served with health insurance and the means to pay for Direct Primary Care out of pocket—including an option to text message my GP directly for urgent issues outside business hours.

In short, I have the good fortune to control most aspects of my daily life, so I could plan around the reality of vaccine side effects. I had sufficient personal resources to fall back on to meet all of my post-vaccination needs. Far too many Americans are less fortunate, many in more than one of the areas I’ve mentioned.

Speaking specifically to the autoimmune-challenged community, I’ve been delighted to find that my second dose of the mRNA vaccine seems to have abruptly ended the prolonged flare I experienced in the four weeks between shots. After feeling much worse due to its side effects than I had in over a year, by the fourth day post-vaccination, I became more energetic—and had less joint pain and stiffness—than I could recall feeling in recent memory. bandage on upper arm

I.e., my RA flare ended abruptly along with my vaccine side effects from the second shot.

Given that vaccination clears lingering symptoms for as many as 41% of COVID long haulers, I was fascinated to observe what could be a related effect in myself after jab #2. Communicating this potential improvement in daily functioning to those who are vaccine hesitant while believing themselves to have had COVID—some of whom never got confirmation of a likely coronavirus infection due to the scarcity of tests early in the pandemic—seems like yet another missed opportunity in public health messaging.

Everyone who wants the economy to rebound fully should take all possible actions to enable workers, especially those at the margins of poverty with limited access to health care, to make, keep, and recover after appointments for inoculation. Full disclosure of the known risks and known benefits—but also realistic potential risks and probable benefits—could bring us closer to herd immunity and full fiscal and medical recovery.

COVID-19 still holds many mysteries for science to uncover. The need to offer accurate information as well as paid time off to over-burdened breadwinners and caregivers so that they can confidently book vaccinations—without risking their livelihood!—isn’t one of them.

America’s front-line, essential workers have already borne more than their fair share of the fight against this pandemic. Today, those who employ these millions should step up with specific support to enable each one to get his or her shots.

* I say “likely” based upon the CDC website stating, for the Pfizer vaccine, “84.7% reported at least one local injection site reaction” and “77.4% reported at least one systemic reaction.” For the Moderna version, they state “[s]ystemic reactions were reported by the majority of vaccine recipients” with over 80% experiencing injection site reactions.